Does Creatine Boost Brain Performance?

Research suggests that creatine in fact can boost brain performance. This article will explain what creatine is, and how it plays a role in improving brain performance, enhancing focus, and overall mental energy. 

Key Takeaways

  1. Creatine may support cognitive performance and can help reduce stress and mental fatigue. 
  2. Creatine supplementation may help improve focus, particularly in individuals who are sleep-deprived.
  3. Creatine may boost mental acuity and alertness by increasing cellular energy.
  4. To reap the benefits of creatine for brain health, proper dosing is crucial and individual needs may vary. 

What is Creatine?

Creatine is a natural occurring compound found in muscle cells. Although our body makes creatine in the liver, kidneys, and pancreas, we also get creatine from foods and supplements. In the body, creatine is synthesized from amino acids and is stored in the muscles and the brain. 

Creatine helps produce energy, especially during high-intensity exercise. On a chemical level, it provides a phosphate group to regenerate adenosine triphosphate (ATP)—the primary energy molecule for our cells. This process is key for both physical performance but also mental performance and brain function (1). 

Many people take creatine supplements to improve their athletic performance and increase lean muscle mass. However, taking creatine can also be beneficial for brain health. 

In fact, the brain uses a significant amount of ATP to function optimally. Taking creatine supplements can be a great way to ensure the brain has the energy it needs, particularly during periods of intense focus or other activities that require a high cognitive demand. 

Does Creatine Improve Brain Performance?

Some research suggests that creatine can improve brain performance. 

Studies suggest that creatine supplements may boost memory and intelligence, particularly under periods of stress. Creatine supplements may be particularly beneficial when people are sleep deprived or facing mental exhaustion. 

While creatine supplements can be beneficial for everyone’s brain health, it may be particularly beneficial for those who follow a largely plant-based diet. 

Many vegetarians and vegans naturally have lower baseline creatine levels because they’re not consuming as much dietary creatine. When these individuals supplement with creatine, there has been a much more noticeable improvement in memory and cognitive performance (2).

Creatine has also shown to be effective in protecting the brain against age-related cognitive decline. Creatine can help counteract the natural reductions in cellular energy production that is common with aging. 

More research is needed to further understand the long-term benefits of creatine supplementation and long term cognitive function. 

Does Creatine Improve Focus?

Creatine may also help improve focus, particularly in situations of high stress or sleep deprivation. 

Some studies suggest that creatine can boost attention span and concentration for individuals who are under-slept. Creatine helps maintain higher levels of ATP, which is essential for performing cognitive tasks, particularly when the brain is fatigued.

Lack of adequate rest naturally reduces focus, but creatine may help counteract the effects of sleep deprivation.

The role that creatine plays on focus is likely linked to its role in energy metabolism. Since the brain needs a continuous supply of ATP to maintain concentration, creatine can help this process (3).

Does Creatine Help With Sleep Deprivation?

While there is some research to suggest that creatine can help with sleep hygiene, more research is needed to further understand the relationship with creatine and sleep. 

It’s likely that creatine can help reduce some of the effects of sleep deprivation. Without enough sleep, there is less ATP in the brain, which makes performing cognitive tasks more difficult. Supplemental creatine can help offset some of the energy deficits caused by sleep deprivation (4).

Some studies suggest that people who take creatine experience improved performance on various cognitive tasks. 

However, it’s important to understand that although creatine may help you feel more focused, creatine supplementation should not be relied on as a substitute for sleep. 

Getting adequate, regular sleep is integral to health and well-being, however, creatine may help maintain mental performance on occasion when you’re unable to get enough sleep. 

More research is needed to better understand the role that creatine plays in sleep deprivation. Early findings are promising that creatine can be helpful for those who experience occasional sleep deprivation. 

Does Creatine Give You More Mental Energy?

Creatine may be able to boost brain power and help increase mental energy. 

Creatine supports brain health by helping produce ATP, regulating neurotransmitters, and promoting mental clarity and stamina.

Individuals who take creatine supplements often report feeling more alert and less mentally tired. Creatine can definitely help sustain energy levels in the brain and allows for longer periods of concentration(5). 

Students and busy professionals can both have demanding schedules and deadlines with mentally demanding tasks at hand. Both of these groups may benefit from creatine supplements to more effectively complete these tasks and perform at their best.

Does Creatine Improve Dopamine?

The relationship between creatine and dopamine is not widely studied. However, it is speculated that creatine may indirectly support dopamine levels by boosting ATP production. 

Dopamine production relies on ATP, and therefore, by increasing ATP availability, it’s thought that dopamine synthesis could be enhanced. The more dopamine there is available in the brain, the more likely someone is to be in a better mood and have increased motivation (6).

Even though there is no direct evidence to suggest that creatine increases dopamine levels, it’s likely that creatine can boost mood and reduce feelings of fatigue. 

It’s clear that more research is needed to further explore whether creatine can directly impact dopamine levels, or if the cognitive benefits of creatine are more so related to increases in cellular energy in the brain.

How Much Creatine Should I Take for My Brain?

When it comes to dosing creatine for brain health, it’s important to keep in mind that individual needs might vary. 

Most studies that look at the relationship between creatine and cognitive performance use the standard dosing of creatine that would be used to boost physical performance. It’s common to take 3-5 grams of creatine daily. However, individual needs can vary depending on various factors such as weight, diet, and baseline creatine levels (7).

For most people, it typically makes sense to start with a lower dose and gradually increase so you can properly assess how you feel as your body gets used to the supplement. 

Some people may choose to start with an initial higher dose such as 10 or even 20 grams of creatine to more quickly saturate the brain. Just like the muscles, the brain can become saturated with creatine. After the initial loading period, a lower maintenance dose of 3-5 grams daily is often appropriate. 

You can check out our oranged flavored creatine monohydrate powder.

It can be helpful to consult with a healthcare professional such as a Registered Dietitian to understand what dosage of creatine is right for you. 

Key Points on Creatine and Brain Performance 

Creatine, a commonly used supplement to boost physical performance, is gaining attention for its role in boosting brain function and cognitive health. 


By increasing ATP available in the brain, creatine can boost brain performance, enhance focus, and increase overall mental energy. 

Research suggests that creatine supplementation can help make the brain more resilient and less impacted by sleep deprivation. This can be particularly beneficial for individuals like students or busy professionals who often have more cognitively demanding work. 

Some research also suggests that creatine may also help to boost mood and motivation, although the exact mechanism is not totally understood.

By boosting cellular energy in the brain, creatine may be a valuable supplement for enhancing brain performance and mental stamina.

A daily dose of 3-5 grams daily is commonly used, however, individual needs may vary.

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